Microporous encapsulated endocrine cell disks, biconcave...

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Tissue

Reexamination Certificate

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C435S325000, C424S556000, C514S866000

Reexamination Certificate

active

07018419

ABSTRACT:
An endocrine cell microdisk or macrodisk containing pancreatic cells for transplantation into an animal body is formed with a lateral extent much greater than its thickness to thereby enhance its diffusional capability. One or more concavities may also be formed therein to further enhance the diffusion of cellular products across the microdisk walls.

REFERENCES:
patent: 5855613 (1999-01-01), Antanavich et al.
patent: 5879709 (1999-03-01), Soon-Shiong et al.
patent: 6165225 (2000-12-01), Antanavich et al.
Yang et al. (Biomaterials, Jan. 1994, vol. 15(2): 113-120.).

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