Microphase separated hydrogels for controlled release of bioacti

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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424 80, 424 81, A61K 922, A61K 952, A61K 3178, A61K 3179

Patent

active

046938877

ABSTRACT:
Novel hydrogel compositions, comprised of a blend of two thermoplastic uncrosslinked polymers, one of which is hydrophobic, and the other hydrophilic, and having a microphase separated morphology are described. These hydrogel compositions are useful as devices for controlling the release rate of bioactive agents, such as therapeutic drugs, antimicrobials, contraceptive agents, or the like, in a biological environment. Depending upon the chemical nature of the agent to be released, its rate of release can be controlled by appropriate selection of the polymeric components of the blend and their relative ratios.

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patent: 4300820 (1981-11-01), Shah
Hasaka et al.
Okano et al.
Nakashima et al.

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