Microparticle switching devices for use in implantable reservoir

Surgery – Controlled release therapeutic device or system – Implanted dynamic device or system

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

604 93, 604250, A61K 922

Patent

active

056432470

ABSTRACT:
A diode device (10) containing a microparticle polymer element (12) is described. Also described are mechanical switching devices that employ the microparticle polymer element.

REFERENCES:
patent: 4140121 (1979-02-01), Kuhl et al.
patent: 4140122 (1979-02-01), Kuhl et al.
patent: 4577642 (1986-03-01), Stokes
patent: 4581624 (1986-04-01), O'Connor
patent: 4639244 (1987-01-01), Rizk et al.
patent: 4705503 (1987-11-01), Dorman et al.
patent: 4787888 (1988-11-01), Fox
patent: 4871680 (1989-10-01), Barraud et al.
patent: 4873088 (1989-10-01), Mayhew et al.
patent: 4886514 (1989-12-01), Maget
patent: 4895719 (1990-01-01), Radhakrishnan et al.
patent: 4912032 (1990-03-01), Hoffman et al.
patent: 5008102 (1991-04-01), York
patent: 5008253 (1991-04-01), Casu et al.
patent: 5019372 (1991-05-01), Folkinen et al.
patent: 5041107 (1991-08-01), Heil, Jr.
patent: 5062841 (1991-11-01), Siegel
patent: 5152758 (1992-10-01), Kaetsu et al.
patent: 5171578 (1992-12-01), Bally et al.
patent: 5188826 (1993-02-01), Chandrasekaran et al.
patent: 5192535 (1993-03-01), Davis et al.
patent: 5226902 (1993-07-01), Bae et al.
patent: 5240713 (1993-08-01), Ayer
patent: 5336057 (1994-08-01), Fukuda et al.
patent: 5400824 (1995-03-01), Gschwendtner et al.
patent: 5417235 (1995-05-01), Wise et al.
patent: 5452878 (1995-09-01), Gravesen et al.
Abe, T., et al., "Synthesis and Characterization of Thermo-Sensitive Polymeric Beads," Journal of Applied Polymer Science 40: 1223-1235 (1990).
Aitken, M.L., and P. Verdugo, "Donnan mechanism of mucin release and conditioning in goblet cells: the role of polyions," Soc. Exp. Biol.: 73-80 (1989).
Annaka, M., and T. Tanaka, "Multiple phases of polymer gels," Nature 355: 430-432 (1992).
Arshady, R., "Microspheres for biomedical applications: preparation of reactive and labelled microspheres," Biomaterials 14(1): 5-15 (1993).
Atkins, T.W., et al., "Incorporation and release of fluorescein isothiocyanate-linked dextrans from a bead-formed macroporous hydrophilic matrix with potential for sustained release," Biomaterials 14(1): 16-20 (1993).
Breckenridge, L.J., and W. Almers, "Currents through the fusion pore that forms during exocytosis of a secretory vesicle," Nature 328: 814-817 (1987).
Breckenridge, L.J., and W. Almers, "Final steps in exocytosis observed in a cell with giant secretory granules," Proc. Natl. Acad. Sci. USA 84: 1945-1949 (1987).
Candau, F., et al., "Kinetic Study of the Polymerization of Acrylamide in Inverse Microemulsion," J. Poly Sci. Part A, 23: 193-214 (1985).
Chevalier, P., et al., "Comparative study on the diffusion of an IgG from various hydrogel beads," Biotechnology Techniques 1(3): 201-206 (1987).
Clark, A.H., and S.B. Ross-Murphy, "Structural and mechanical properties of biopolymer gels," Adv. in Polymer Sci. 83: 57-142 (1987).
Curran, M.J., and M.S. Brodwick, "Ionic Control of the Size of the Vesicle Matrix of Beige Mouse Mast Cells," J. Gen. Physiol. 98: 771-790 (1991).
Duzgunes, N., and P.L. Felgner, "Intracellular Delivery of Nucleic Acids and Transcription Factors by Cationic Liposomes," Methods in Enzymology 221: 303-306 (1993).
Edwards, S.F., "Sixth International Congress of Biorheology Plenary Lecture: The Theory of Macromolecular Networks," Biorheology 23: 589-603 (1986).
Fernandez, J.M., et al., "Reversible condensation of mast cell secretory products in vitro," Biophys. J. 59: 1022-1027 (1991).
Fujimoto, K., et al., "Interactions between Thermosensitive Hydrogel Microspheres and Proteins," Journal of Intelligent Material Systems and Structures 4: 184-189 (1993).
Fujimoto, K., et al., "Fluorescence Analysis for Thermosensitive Hydrogel Microspheres," Polymer International 30: 237-241 (1993).
Gehrke, S.H., and E.L. Cussler, "Mass transfer in pH-sensitive hydrogels," Chem. Eng. Sci. 44: 559-566 (1989).
Hoffman, A.S., "Thermally reversible hydrogels containing biologically active species," in Polymers in Med. III (Migliarese, C., et al., eds., Elsevier Sci. Pub., Amsterdam, pp. 161-167, 1988).
Hoffman, A.S., "Molecular Bioengineering of Biomaterials in the 1990s and Beyond: A Growing Liaison of Polymers with Molecular Biology," Artificial Organs 16(1): 43-49 (1992).
Hoffman, A.S., "Environmentally Sensitive Polymers and Hydrogels. Smart Biomaterials," MRS Bulletin Sep.: 42-46 (1991).
Hoffman, A.S., "Applications of Thermally Reversible Polymers and Hydrogels in Therapeutics and Diagnostics," Journal of Controlled Release 6: 297-305 (1987).
Hoke, F., "`Smart` Materials Research Expands Beyond Defense Arena," The Scientist, Apr. 27: 13 (1992).
Huang, Y., et al., "Synthesis and characterization of bisacrylamide microgels containing sulfo groups," Makromol. Chem. 186: 273-281 (1985).
Ilmain, F., et al., "Volume transition in a gel driven by hydrogen bonding," Nature 349: 400-401 (1991).
Ishihara, K., et al., "Controlled release of organic substances using polymer membrane with responsive function for amino compounds," J. Appl. Polym. Sci. 29: 211-217 (1984).
Kajiwara, K., and S.B. Ross-Murphy, "Synthetic gels on the move," Nature 355: 208-209 (1992).
Kawaguchi, H., et al., "Preparation and Modification of Monodisperse Hydrogel Microspheres," Polymer International 30: 225-231 (1993).
Kerkam, K., et al., "Liquid crystallinity of natural silk secretions," Nature 349: 596-598 (1991).
Kibat, P.G., et al., "Enzymatically activated microencapsulated liposomes can provide pulsatile drug release," The FASEB Journal 4: 2533-2539 (1990).
Kim, T.D., et al., "Studies on Liposome-Encapsulated Heparin," Thrombosis Research 43: 603-612 (1986).
Kishi, R., and Y. Osada, "Reversible Volume Change of Microparticles in an Electric Field," J. Chem. Soc., Faraday Trans. 1, 85(3): 655-662 (1989).
Klein, J., et al., "Forces between polymer-bearing surfaces undergoing shear," Nature 352: 143-145 (1991).
Kokufata, E., et al., "Saccharide-sensitive phase transition of a lectin-loaded gel," Nature 351: 302-304 (1991).
Kreuter, J., "Nanoparticles--Preparation and Applications," Chapter 6 from Microcapsules and Nanoparticles in Medicine and Pharmacy (M. Donbrow, ed., CRC Press Florida, 1992, pp. 125-148 ).
Kuhn, W., et al., "Reversible dilation and contraction by changing the state of ionization of high-polymer acid networks," Nature 165: 514-516 (1950).
Kwon, I.C., et al., "Electrically erodible polymer gel for controlled release of drugs," Nature 354: 291-293 (1991).
Kwon, G.S., et al., "Release of proteins via ion exchange from albumin-heparin microspheres," Journal of Controlled Release 22: 83-94 (1992).
Langer, R., "New Methods of Drug Delivery," Science 249: 1527-1532 (1990).
Lasic, D.D., et al., "Gelation of liposome interior. A novel method for drug encapsulation," FEBS Letters 312(2,3): 255-258 (1992).
Miyamoto, T., and K. Shibayama, "Free-volume model for ionic conductivity in polymers," J. Appl. Phys. 44(12): 5372-5374 (1973).
Monck, J.R., et al., "Is swelling of the secretory granule matrix the force that dilates the exocytotic fusion pore?" Biophys. J. 59: 39-47 (1992).
Nakamae, K., et al., "Swelling behavior of hydrogels containing phosphate groups," Makromol. Chem. 193: 983-990 (1992).
Nanavati, C., et al., "The Secretory Granule Matrix: A Fast-Acting Smart Polymer," Science 259: 963-965 (1993).
Nanavati, C., Doctoral Dissertation: "Excytosis: An Analysis of the Properties of the Fusion Pore and the Secretory Granule Matrix," Nov., 1992.
Okahata, Y., et al., "Thermoselective permeation from a polymer-grafted capsule membrane," Macromolecules 19: 493-494 (1986).
Okano, T., et al., "Thermally On-Off Switching Polymers for Drug Permeation and Release," Journal of Controlled Release 11: 255-265 (1990).
Okubo, M., and T. Nakagawa, "Preparation of micron-size mono-disperse polymer particles having highly crosslinked structures and vinyl groups by seeded polymerization of divinylbenzene using the dynamic swelling method," Colloid Polym. Sci. 270: 853-858 (1992).
Osada, Y., "Conversion of Chemical Into Mechanical Energy by Synthetic Polymers (Chemomechanical Systems)," Advances in Polymer Science 82: 1-46 (1987).
Osada, Y., et al., "A polymer gel with electrically dr

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Microparticle switching devices for use in implantable reservoir does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microparticle switching devices for use in implantable reservoir, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microparticle switching devices for use in implantable reservoir will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-592741

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.