Microorganisms suitable for producing compounds containing a ter

Details Microorganisms suitable for producing compounds containing a ter Microorganisms suitable for producing compounds containing a ter

1991-04-01

1992-12-22

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435123, 4351723, 435281, C12N 121

Patent

active

051734281

ABSTRACT:
This invention relates to a process for the microbiological production of compounds containing a terminal hydroxyl or epoxy group from an aliphatic substrate or a substrate with an aliphatic side chain, using microorganisms genetically engineered so that they have retained their capacity to perform the terminal oxidation of the substrate, but are no longer able to convert the resulting oxidation product further to any significant extent. Preferred substrates are n-alkanes, n-alkenes, and n-alkadienes containing 6-12 carbon atoms. Preferred micro-organisms are genetically engineered Pseudomonas oleovorans and Pseudomonas putida strains lacking an active plasmidic alkanol-dehydrogenase gene. The invention also relates to micro-organisms thus genetically engineered.

REFERENCES:
patent: 3813316 (1974-05-01), Chakrabarty et al.

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