Microorganisms immobilized with hydrolysis resistant polyurethan

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435180, 435182, C12P 1320, C12N 1108, C12N 1104

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active

044566859

ABSTRACT:
Foams having aspartase-producing microorganisms bound to the foam are made from polyurethane prepolymers which are capped with polyisocyanates, including diisocyanates, derived from methylene-bis (phenyl isocyanate) which is commonly known as MDI. These MDI based foams are hydrolysis resistant as compared to the previously used TDI based foams. The foams can be used to produce L-aspartic acid under high pH conditions.

REFERENCES:
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patent: 4312946 (1982-01-01), Wood et al.
patent: 4342834 (1982-08-01), Wood et al.
patent: 4377645 (1983-03-01), Guthrie et al.
patent: 4384050 (1983-05-01), Guthrie
patent: 4384051 (1983-05-01), Guthrie
Fusee et al., Immobilization of Escherichia coli Cells Containing Aspartase Activity with Polyurethane and Its Application for L-Aspartic Acid Production, Applied and Environmental Microbiology, vol. 42, No. 4, 1981 (pp. 672-676).

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