Microorganisms and methods for overproduction of DAHP by...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S252300, C435S320100, C435S069100, C435S193000, C435S194000, C435S041000, C435S106000, C435S108000

Reexamination Certificate

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10289788

ABSTRACT:
Genetic elements comprising expression vectors and a gene coding for phosphoenol pyruvate synthase is utilized to enhance diversion of carbon resources into the common aromatic pathway and pathways branching therefrom. The overexpression of phosphoenol pyruvate synthase increases DAHP production to near theoretical yields.

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patent: 6319696 (2001-11-01), Kishino et al.
patent: 6706516 (2004-03-01), Liao
Patnaik et al., Applied and Environmental Microbiology 60(11):3903-3908, 1994.
Seffernick et al. , J. Bacteriol. 183(8):2405-2410, 2001.
Witkowski et al. , Biochemistry 38:11643-11650, 1999.
Patnaik et al., J. Bacteriol. 174(23):7527-7532, 1992.

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