Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1995-12-14
1997-12-02
Grives, Eric
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
4352523, 43525233, 435325, C12N 121, C12N 510, C12P 1718
Patent
active
056935048
ABSTRACT:
A microorganism resistant to a nicotinic acid analogue, which has a plasmid containing part or whole of a biotin operon; and a process for producing biotin, which comprises culturing a microorganism described above in a medium to produce and accumulate biotin in the medium, and collecting biotin.
REFERENCES:
patent: 5374554 (1994-12-01), Komatsubara et al.
Tritz, in Escherichia coli & Salmonella typhimurium, Cellular and Molecular Biology, Neidhardt et al. (eds.), Am. Soc. Microbiol., Washington, DC, pp. 557-563, 1987.
McGraw-Hill Dictionary of Chemical Terms, Sybil P. Parker (ed.), McGraw-Hill Book Co., New York, NY, 1985.
Fujisawa et al., "Biotin Production by bioB Transformants of a Bacillus sphaericus Mutant Resistant to 1-(2'-Thenoyl)-3,3,3-trifluoroacetone, an Electron Transport Inhibitor", Biosci. Biotech. Biochem., vol. 58 (6), pp. 1018-1022, 1994.
Sakurai et al., "Improvement of a d-biotin-hyperproducing recombinant strain of Serratia marcescens" Journal of Biotechnology, vol. 36 pp. 63-73, 1994.
Sakurai et al., "Construction of a Biotin-Overproducing Strain of Serratia marcescens" Applied and Environmental Microbiology, vol. 59, No. 9, pp. 2857-2863, Sep. 1993.
Ifuku Ohji
Kanzaki Naoyuki
Kimura Hiroyuki
Matsui Junji
Nakahama Kazuo
Grives Eric
Shiseido Company Limited
Takeda Chemical Industries Ltd.
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