Microorganism of the genus Corynebacterium having enhanced...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

Reexamination Certificate

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C435S243000, C435S252100, C536S023100

Reexamination Certificate

active

07575899

ABSTRACT:
The present invention provides a microorganism that belongs to the genusCorynebacteriumand has an inactivated inherent NCgl2053 dehydrogenase gene, and a method of producing L-lysine using the same. By using the microorganism, the yield of L-lysine is increased since an inherent NCgl2053 dehydrogenase gene is inactivated. According to the method, L-lysine can be produced with high yield.

REFERENCES:
patent: 5766925 (1998-06-01), Sugimoto et al.
patent: 6872553 (2005-03-01), Eikmanns et al.
patent: 01/00844 (2001-01-01), None
Nakagawa et al., “TheCorynebacterium glutamicumgenome: features and impacts on biotechnological processes.” Appl Microbiol Biotechnol. Aug. 2003:62(2-3):99-109. Epub May 13, 2003 English abstract only, with related NCBI sequence transmission.
Last Non-Final Rejection issued by the Korean Intellectual Property Office for KR 10-2005-0115906 with English translation. 5 pages.
Ikeda et al., “TheCorynebacterium glutamicumgenome: features and impacts on biotechnological processes”, Appl Microbio Biotechnol, 2003, vol. 62, pp. 99-109; XP002419971.
Kalinowski et al., “The completeCorynebacterium glutamicumATCC 13032 genome sequence . . . ”, Journal of Biotechnology, 2003, vol. 104, pp. 5-25; XP001184752.

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