Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-12-28
2011-11-01
Raghu, Ganapathirama (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S106000, C435S252320, C435S252300, C435S471000, C435S320100
Reexamination Certificate
active
08048650
ABSTRACT:
The present invention relates to a microorganism ofCorynebacteriumgenus having enhanced L-lysine productivity and a method of producing L-lysine using the same. More particularly, the present invention relates to a recombinant microorganism ofCorynebacteriumgenus having enhanced L-lysine productivity by inactivating endogenous NCgI 1090 gene having the amino acid sequence containing repeated aspartate residues and a method of producing L-lysine using the same.
REFERENCES:
patent: 6221636 (2001-04-01), Hayakawa et al.
patent: 6746855 (2004-06-01), Kreutzer et al.
patent: 6872553 (2005-03-01), Eikmanns et al.
patent: 6913909 (2005-07-01), Ziegler et al.
patent: 6962989 (2005-11-01), Pompejus et al.
patent: 7160711 (2007-01-01), Bathe et al.
patent: 2002/0192674 (2002-12-01), Hermann et al.
patent: 2002/0197605 (2002-12-01), Nakagawa et al.
patent: 2005/0153402 (2005-07-01), Pompejus et al.
patent: 2008/0293100 (2008-11-01), Wendisch et al.
patent: 2010/0015673 (2010-01-01), Koo et al.
patent: 2010/0129884 (2010-05-01), Cho et al.
patent: 2010/0330624 (2010-12-01), Jang et al.
patent: 101 10 760 (2001-08-01), None
patent: H07-121228 (1995-05-01), None
patent: HEI 7-121228 (1995-12-01), None
patent: 1020050065712 (2005-06-01), None
patent: 10-2008-025355 (2008-03-01), None
patent: WO 02/053707 (2002-07-01), None
patent: WO 2005/121349 (2005-12-01), None
patent: WO 2007/039532 (2007-04-01), None
Tzvetkov et al. (Jul. 2003) Microbiology 149(7):1659-1673, “Genetic dissection of trehalose biosynthesis inCorynebacterium glutamicum: Inactivation of trehalose production leads to impaired growth and altered cell wall lipid composition”.
European Search Report issued Dec. 30, 2009 in PCT/KR2007/006935.
EP Search Report issued Feb. 18, 2010 in EP application serial No. 07851817.2.
Database UnitProt [Online] Jul. 5, 2004, “SubName: Full=Putative uncharacterized protein”.
Ikeda and Nakagawa (Aug. 2003) Appl Microbiol Biotechnol 62: 99-109, “TheCorynebacterium glutamicumgenome: features and impacts on biotechnological processes”.
Mitsuhashi et al. (Nov. 2006) Biosci. Biotechnol. Biochem. 70(11): 2803-2806, “Disruption of Malate:Quinone Oxidoreductase Increases L-Lysine Production byCorynebacterium glutamicum”.
Eggeling (1994) Amino Acids 6:261-272, “Biology of L-lysine overproduction byCorynebacterium glutamicum”.
International Written Opinion dated Jan. 24, 2008 from PCT/KR2007/006936.
International Search Report dated Jan. 24, 2008 from PCT/KR2007/006936.
International Written Opinion dated Jan. 24, 2008 from PCT/KR2007/006935.
International Search Report dated Jan. 24, 2008 from PCT/KR2007/006935.
U.S. Appl. No. 12/867,649, filed Aug. 13, 2010, Jang et al.
Hayes, Finbarr (2003) Annu. Rev. Genet. 37:3-29, “Transposon-Based Strategies for Microbial Functional Genomics and Proteomics”.
Mormann (Aug. 10, 2006) BMC Genomics, 7:205, doi:10.1186/1471-2164-205, “Random mutagenesis inCorynebacterium glutamicumATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway”.
Peters-Wendisch et al. (Nov. 2005) Applied and Environmental Microbiology, 71(11):7139-7144, “Metabolic Engineering ofCorynebacterium glutamicumfor L-Serine Production”.
Tsuge et al. (2005) Microbiology 151:501-508, “A New Insertion Sequence, IS14999, fromCorynebacterium glutamicum”.
Office Action issued Jan. 7, 2011 in U.S. Appl. No. 12/518,572.
Choi Jong-soo
Kim Hyo-jin
Koo Hyun-min
Lim Sang-jo
Moon Jun-ok
CJ Cheiljedang Corporation
Raghu Ganapathirama
Swanson & Bratschun L.L.C.
LandOfFree
Microorganism of Corynebacterium genus having enhanced... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Microorganism of Corynebacterium genus having enhanced..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microorganism of Corynebacterium genus having enhanced... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4296656