Microorganism mutant conversion of sterols to androsta-4-ene-3,1

Details Microorganism mutant conversion of sterols to androsta-4-ene-3,1 Microorganism mutant conversion of sterols to androsta-4-ene-3,1

1980-09-08

1982-08-17

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

C12P 3316

Patent

active

043450300

ABSTRACT:
Mutant which is used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield predominantly androst-4-ene-3,17-dione (AD) and small amounts of androsta-1,4-diene-3,17-dione (ADD). AD is a valuable intermediate to make useful steroids.

REFERENCES:
patent: 3388042 (1968-06-01), Arima et al.
patent: 3684656 (1972-08-01), van der Waard
Mamoli et al., Ber 70, pp. 470 & 471 and 2079-2982 (1937).

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