Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound having a 1-thia-5-aza-bicyclo
Patent
1986-06-16
1990-02-06
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound having a 1-thia-5-aza-bicyclo
435119, 435161, 435162, 435177, 435179, 435180, C12P 3506, C12P 1718, C12P 714, C12N 1102
Patent
active
048988170
ABSTRACT:
An improved repetitive, batch-type fermentation process is provided. It includes a first, non-repetitive step of forming a support bearing a film of live and reproductive microorganisms immobilized thereon, e.g. using a cloth support. Then, the process involves the steps of freely suspending and stirring small segments of support cloth bearing a fixed film of live and reproductive microorganisms immobilized thereon within a fermenter containing suitable nutrient liquor to carry out a fermentation process, whereby the microorganisms produce a fermented liquor; withdrawing fermented liquor from the fermenter while retaining the support cloth within the fermenter; adding fresh nutrient to the fermenter containing the support cloth bearing the fixed film of live and reproductive microorganisms immobilized thereon; and repeating the above steps a plurality of times. This provides an improved batch-type fermentation process which minimizes the problems of start-up and which can be readily scaled-up and automated.
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Joshi Sushama
Yamazaki Hiroshi
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