Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1985-05-02
1988-06-28
Tarcza, John E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
C12Q 116
Patent
active
047538783
ABSTRACT:
A technique for identifying an unknown microorganism, in which technique a specimen of the unknown microorganism is prepared to which a radioactive emissive agent has been added that is actively incorporated into the products of metabolism of the microorganism to produce a mix of radioactive peptide or protein emissive products in a manner that depends on the metabolic mechanism of the microorganism. The peptide or protein emissive products in the mix resulting from the preparation of the specimen are then separated. The separated emissive products are detected by sensing the emission from the products to provide an electrical signal whose wave pattern is indicative of the identity of the microorganism. This wave pattern is compared in a computer with patterns stored therein representing a collection of known microorganisms.
REFERENCES:
patent: 4521512 (1985-06-01), Silman
patent: 4526865 (1985-07-01), Silman
Metzler, "Biochemistry" Academic Press (1977) NY, pp. 124-125.
Winkelman et al "Automatic Calculation of Densitometer Scans of Electrical Strips" Clinical Chemistry 15(8) pp. 708-711 (1969).
AMB Systems Corp.
Ebert Michael
Tarcza John E.
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