Microorganism having all the identifying characteristics of absi

Details Microorganism having all the identifying characteristics of absi Microorganism having all the identifying characteristics of absi

1997-02-13

1998-09-29

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

435148, 435155, 514569, 562462, C12N 114, C12P 726, C12P 702, C07C 5976

Patent

active

058145125

ABSTRACT:
Purpurogallin derivatives are produced useful for inhibiting catecholamine-O-methyltransferase. The derivative, 8-O-methylpurpurogallincarboxylic acid, is produced with a microorganism of the genus Absidia having all the identifying characteristics of FERM BP-4599. A pharmaceutical composition containing 8-O-methylpurpurogallincarboxylic acid or an ester or salt thereof is useful in treating Parkinson's diseases.

REFERENCES:
Gams et al., Compendium of Soil Fungi, vol. 1, Academic Press, London, pp. 7-15 (1980).
Abstract from Report of the J. Chem. Soc. of Japan 77, 305 (1956).
Advances in Neurology, vol. 53 pp. 497-503 (1990).

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