Microorganism having ability to convert sterol into...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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Details

C435S052000, C435S053000, C435S055000, C435S252100, C435S252300

Reexamination Certificate

active

10477447

ABSTRACT:
Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain ofMycobacterium fortuitumATCC 29472,Mycobacterium fortuitumEUG-119, a method for preparation of the mutant and use thereof in preparing AD and ADD. The mutant of the present invention has an excellent ability to convent sterol into AD and ADD which are steroid hormone precursors, compared with the known microorganisms and accordingly, is very useful for mass production of steroid hormones.

REFERENCES:
patent: 4100027 (1978-07-01), Weber et al.
patent: 4170518 (1979-10-01), Weber et al.
patent: 4293644 (1981-10-01), Wovcha et al.
patent: 4293645 (1981-10-01), Wovcha et al.
patent: 4345029 (1982-08-01), Wovcha et al.
patent: 4397946 (1983-08-01), Imada et al.
patent: 5418145 (1995-05-01), Weber et al.
patent: 5516649 (1996-05-01), Weber et al.
patent: 2004/0152153 (2004-08-01), Noh et al.
patent: 54059395 (1979-05-01), None
patent: 56120698 (1981-09-01), None

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