Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2007-08-21
2007-08-21
Lilling, Herbert J. (Department: 1657)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S052000, C435S053000, C435S055000, C435S252100, C435S252300
Reexamination Certificate
active
10477447
ABSTRACT:
Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism and use thereof, and more particularly, a mutant strain ofMycobacterium fortuitumATCC 29472,Mycobacterium fortuitumEUG-119, a method for preparation of the mutant and use thereof in preparing AD and ADD. The mutant of the present invention has an excellent ability to convent sterol into AD and ADD which are steroid hormone precursors, compared with the known microorganisms and accordingly, is very useful for mass production of steroid hormones.
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Kim Myung-Kuk
Noh Seung-Kwon
Park Kyung-Moon
Park Sang-Ok
Yoon Won-Tae
Drinker Biddle & Reath LLP
Eugene Science Inc.
Lilling Herbert J.
Monaco Daniel A.
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