Solid material comminution or disintegration – Processes – By operations other than force of contact with solid surface
Reexamination Certificate
2005-09-13
2005-09-13
Rosenbaum, Mark (Department: 3725)
Solid material comminution or disintegration
Processes
By operations other than force of contact with solid surface
C241S002000, C241S301000, C435S259000, C435S820000
Reexamination Certificate
active
06942169
ABSTRACT:
A method and device for performing lysing on a cell-containing fluid, in which the fluid flows through a vibrating micromachined tube to physically rupture the cell walls (mechanical lysis), and/or to mix, agitate or homogenize the fluid during chemical lysis, and/or to mix, agitate or homogenize the lysate for analysis or other processing after lysing. The tube includes a freestanding portion spaced apart from a surface of a substrate on which the tube is formed. The device further includes means for vibrating the freestanding portion of the tube at a level sufficient to rupture the walls of cells in a fluid flowing through the freestanding portion (for mechanical lysing) or to mix the fluid and a chemical lysing additive within the freestanding portion (for chemical lysing).
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Integrated Sensing Systems
Rosenbaum Mark
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