Microfluidization of radioactive calcium/oxyanion-containing par

Details Microfluidization of radioactive calcium/oxyanion-containing par Microfluidization of radioactive calcium/oxyanion-containing par

1995-04-11

1996-10-01

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Coated, impregnated, or colloidal particulate

424602, 424639, 424643, 424648, 424646, 423700, 1286534, A61K 5100

Patent

active

055609023

ABSTRACT:
Methods of preparing solid apatite particles using a microfluidizer, for use in medical diagnostic imaging such as magnetic resonance imaging, X-ray, and ultrasound. The desired apatite particles are synthesized, passed through a microfluidizer, and purified to remove excess base, salts, and other materials used to synthesize the particles. The microfluidizer causes two high pressure streams to interact at ultra high velocities in a precisely defined microchannel. Microfluidization of preparations causes small (<5 .mu.m) and uniform particles to be formed. Coating and purifying (especially by tangential flow filtration) the particles improves particle stability.

REFERENCES:
patent: 5342609 (1994-08-01), Meeh et al.
patent: 5344640 (1994-09-01), Deutsch et al.
patent: 5419892 (1995-05-01), Cacheris et al.

Affiliated with

Also associated with

Rating

Microfluidization of radioactive calcium/oxyanion-containing par does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microfluidization of radioactive calcium/oxyanion-containing par, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfluidization of radioactive calcium/oxyanion-containing par will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1500546