Microfluidic method for nucleic acid purification and processing

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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Details

435 912, 435 793, 536 2532, 536 254, C12Q 168, C12P 1934, C07H 2100

Patent

active

060748273

ABSTRACT:
Integrated microfluidic devices comprising at least an enrichment channel and a main electrophoretic flowpath are provided. In the subject integrated devices, the enrichment channel and the main electrophoretic flowpath are positioned so that waste fluid flows away from said main electrophoretic flowpath through a discharge outlet. The subject devices find use in a variety of electrophoretic applications, including clinical assays, high throughput screening for genomics and pharmaceutical applications, point-or-care in vitro diagnostics, molecular genetic analysis and nucleic acid diagnostics, cell separations, and bioresearch generally.

REFERENCES:
patent: 4908112 (1990-03-01), Pace
patent: 5296114 (1994-03-01), Manz
patent: 5726026 (1998-03-01), Wilding et al.

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