Microfluidic flow manipulation device

Details Microfluidic flow manipulation device Microfluidic flow manipulation device

2008-04-21

2010-02-09

Sorkin, David L (Department: 1797)

Agitating

Having specified feed means

Plural related feeders having separate outlets to mixing...

C366S337000, C366S341000, C366SDIG003, C137S896000

Reexamination Certificate

active

07658536

ABSTRACT:
Disclosed is an apparatus and method for the mixing of two microfluidic channels wherein several wells are oriented diagonally across the width of a mixing channel. The device effectively mixes the confluent streams with electrokinetic flow, and to a lesser degree, with pressure driven flow. The device and method may be further adapted to split a pair of confluent streams into two or more streams of equal or non-equal concentrations of reactants. Further, under electrokinetic flow, the surfaces of said wells may be specially coated so that the differing electroosmotic mobility between the surfaces of the wells and the surfaces of the channel may increase the mixing efficiency. The device and method are applicable to the steady state mixing as well as the dynamic application of mixing a plug of reagent with a confluent stream.

REFERENCES:
patent: 3226036 (1965-12-01), Grahn
patent: 3788557 (1974-01-01), Breunsbach
patent: 5811062 (1998-09-01), Wegeng et al.
patent: 5900130 (1999-05-01), Benvegnu et al.
patent: 6632655 (2003-10-01), Mehta et al.
patent: 2004/0262223 (2004-12-01), Strook et al.

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