Microfluidic chip for high-throughput screening and...

Details Microfluidic chip for high-throughput screening and... Microfluidic chip for high-throughput screening and...

2004-10-04

2009-06-09

Griffin, Walter D (Department: 1797)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C422S105000, C435S287100, C435S287200

Reexamination Certificate

active

07544507

ABSTRACT:
Disclosed is a micro-fluidic chip for high-throughput screening and high-throughput assay, in which its structure is improved, thereby enhancing the efficiency of high-throughput screening and high-throughput assay. The micro-fluidic chip includes a well for isolating a specimen. The well can be arranged in a one- or two-dimension. A specimen-isolating means is disposed above the well and is movable upwards and downwards. An opening and closing means for moving the specimen-isolating means upwards and downwards is disposed above the specimen-isolating means. An inlet for injection the specimen and an outlet for discharging an excess of the injected specimen are provided. A reagent-injecting passage for injecting a reagent and a reagent-discharging passage for discharging the reagent are also provided.

REFERENCES:
patent: 2003/0215941 (2003-11-01), Campbell et al.
patent: 2004/0175708 (2004-09-01), Caillat et al.
Kwang-Seok Yun and Euisik Yoon, A Micro/Nano-Fluidic Chip-Based Micro-Well Array for High-Throughput Cellanalysis and Drug Screening, Micro Total Analysis Systems 2003, Oct. 5-9, 2003, p. 861-p. 864. vol. 1. The Transducers Research Foundation, Squaw Valley, California, USA.

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