Microfluidic chemostat

Chemistry: molecular biology and microbiology – Apparatus – Bioreactor

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07407799

ABSTRACT:
A chemostat is described that includes a growth chamber having a plurality of compartments. Each of the compartments may be fluidly isolated from the rest of the growth chamber by one or more actuatable valves. The chemostat may also include a nutrient supply-line to supply growth medium to the growth chamber, and an output port to remove fluids from the growth chamber. Also, a method of preventing biofilm formation in a growth chamber of a chemostat is described. The method may include the steps of adding a lysis agent to a isolated portion of the growth chamber, and reuniting the isolated portion with the rest of the growth chamber.

REFERENCES:
patent: 3570515 (1971-03-01), Kinner
patent: 3747628 (1973-07-01), Holster et al.
patent: 4046159 (1977-09-01), Pegourie
patent: 4119368 (1978-10-01), Yamakazi
patent: 4153855 (1979-05-01), Feingold
patent: 4245673 (1981-01-01), Bouteille et al.
patent: 4434704 (1984-03-01), Surjaatmadja
patent: 4898582 (1990-02-01), Faste
patent: 4992312 (1991-02-01), Frisch
patent: 5085562 (1992-02-01), Van Lintel
patent: 5088515 (1992-02-01), Kamen
patent: 5096388 (1992-03-01), Weinberg
patent: 5126115 (1992-06-01), Fujita et al.
patent: 5164558 (1992-11-01), Huff et al.
patent: 5171132 (1992-12-01), Miyazaki
patent: 5224843 (1993-07-01), Van Lintel
patent: 5259737 (1993-11-01), Kamisuki et al.
patent: 5265327 (1993-11-01), Faris et al.
patent: 5290240 (1994-03-01), Horres, Jr.
patent: 5336062 (1994-08-01), Richter
patent: 5346372 (1994-09-01), Naruse et al.
patent: 5375979 (1994-12-01), Trah
patent: 5376252 (1994-12-01), Ekstrom
patent: 5400741 (1995-03-01), DeTitta et al.
patent: 5423287 (1995-06-01), Usami et al.
patent: 5529465 (1996-06-01), Zengerle et al.
patent: 5593130 (1997-01-01), Hansson et al.
patent: 5595650 (1997-01-01), Manz
patent: 5642015 (1997-06-01), Whitehead et al.
patent: 5659171 (1997-08-01), Young et al.
patent: 5660370 (1997-08-01), Webster
patent: 5681024 (1997-10-01), Lisec et al.
patent: 5705018 (1998-01-01), Hartley
patent: 5759014 (1998-06-01), Van Lintel
patent: 5775371 (1998-07-01), Pan et al.
patent: 5779868 (1998-07-01), Parce et al.
patent: 5788468 (1998-08-01), Dewa et al.
patent: 5836750 (1998-11-01), Cabuz
patent: 5842787 (1998-12-01), Kopf-Sill et al.
patent: 5875817 (1999-03-01), Carter
patent: 5876187 (1999-03-01), Forster et al.
patent: 5932799 (1999-08-01), Moles
patent: 5942443 (1999-08-01), Parce et al.
patent: RE36350 (1999-10-01), Swedberg et al.
patent: 6007309 (1999-12-01), Hartley
patent: 6043080 (2000-03-01), Lipshutz et al.
patent: 6054277 (2000-04-01), Furcht et al.
patent: 6107044 (2000-08-01), Nikiforov
patent: 6123769 (2000-09-01), Sanjoh
patent: 6155282 (2000-12-01), Zachary et al.
patent: 6174365 (2001-01-01), Sanjoh
patent: 6296673 (2001-10-01), Santarsiero et al.
patent: 6345502 (2002-02-01), Tai et al.
patent: 6408878 (2002-06-01), Unger et al.
patent: 6409832 (2002-06-01), Weigl et al.
patent: 6508988 (2003-01-01), Van Dam et al.
patent: 6509188 (2003-01-01), Trosch et al.
patent: 6581441 (2003-06-01), Paul
patent: 6596545 (2003-07-01), Wagner et al.
patent: 6599736 (2003-07-01), McCaskill et al.
patent: 6627076 (2003-09-01), Griffiths
patent: 6653124 (2003-11-01), Freeman
patent: 6662818 (2003-12-01), Paul et al.
patent: 6664104 (2003-12-01), Pourahmadi et al.
patent: 6677131 (2004-01-01), Yuen
patent: 6716620 (2004-04-01), Bashir et al.
patent: 6752922 (2004-06-01), Huang et al.
patent: 6767706 (2004-07-01), Quake et al.
patent: 2001/0027745 (2001-10-01), Weigl et al.
patent: 2002/0037499 (2002-03-01), Quake et al.
patent: 2002/0145231 (2002-10-01), Quake et al.
patent: 2002/0158022 (2002-10-01), Huang et al.
patent: 2002/0164816 (2002-11-01), Quake et al.
patent: 0 592 094 (1994-04-01), None
patent: 0 703 364 (1996-03-01), None
patent: 0 706 004 (1996-04-01), None
patent: 0 779 436 (1997-06-01), None
patent: 0 829 360 (1998-03-01), None
patent: 0 845 603 (1998-06-01), None
patent: 0 999 055 (2000-05-01), None
patent: 2 155 152 (1985-09-01), None
patent: 2 308 460 (1997-06-01), None
patent: WO 98/07069 (1998-02-01), None
patent: WO 99/00655 (1999-01-01), None
patent: WO 99/04361 (1999-01-01), None
patent: WO 99/17093 (1999-04-01), None
patent: WO 99/52633 (1999-10-01), None
patent: WO 00/00678 (2000-01-01), None
patent: WO 00/43748 (2000-07-01), None
patent: WO 00/60345 (2000-10-01), None
patent: WO 01/09595 (2001-02-01), None
patent: WO 01/09595 (2001-02-01), None
patent: WO 02/60582 (2002-08-01), None
patent: WO 03/037781 (2003-05-01), None
“Biochips,” Nature Biotechnology, vol. 18, Supplement 2000, pp. IT43-IT44, 2000.
“Chapter 9: Microfluidic Devices,” Micromachined Transducers Sourcebook, pp. 779-882, 1998.
“Electro Microfluidic Dual In-Line Package (EMDIP),” Sandia National Laboratories, 2 pages, no date.
“Last Chance For Micromachines,” The Economist Technology Quarterly, printed from website http://www.economist.com/science/displayStory.cfm?Story—ID=442930 on Jan. 25, 2001, 8 pages, Dec. 7, 2000.
“The Liver Chip,” Technology Review, pp. 64-67, Mar. 2003.
Ahn, Chong H. et al., “Fluid Micropumps Based On Rotary Magnetic Actuators,” Proceedings of 1995 IEEE Micro Electro Mechanical Systems Workshop (MEMS '95), Amsterdam, Netherlands, pp. 408-412, Jan. 29-Feb. 2, 1995.
Anderson, Rolfe C. et al., “Microfluidic Biochemical Analysis System,” Transducers '97, 1997 International Conference on Solid-State Sensors and Actuators, Chicago, Illinois, pp. 477-480, Jun. 16-19, 1997.
Angell, James B. et al., “Silicon Micromechanical Devices,” Scientific American, pp. cover, 44-55, Apr. 1983.
Armani, Deniz et al., “Re-Configurable Fluid Circuits By PDMS Elastomer Micromachining,” IEEE Int. Conf. MIcro Electro Mech. Syst. Tech. Digest, vol. 12, pp. 222-227, 1999.
Ballantyne, J. P. et al., “Selective Area Metallization By Electron-Beam Controlled Direct Metallic Deposition,” J. Vac. Sci. Technol., vol. 10, No. 6, pp. 1094-1097, Nov. 1973.
Benard, W. L. et al., “A Titanium-Nickel Shape-Memory Alloy Actuated Micropump,” Transducers '97, 1997 International Conference on Solid-State Sensors and Actuators, Chicago, Illinois, pp. 361-364, Jun. 16-19, 1997.
Black, Harvey, “Tiny Technology Promises Tremendous Profits,” The Scientist, vol. 15, No. 21, 4 pages, Oct. 29, 2001.
Bloomstein, T. M. et al., “Laser-Chemical Three-Dimensional Writing For Microelectromechanics And Application To Standard-Cell Microfluidics,” J. Vac. Sci. Technol. B, vol. 10, No. 6, pp. 2671-2674, Nov. 1992.
Bousse, Luc et al., “Electrokinetically Controlled Microfluidic Analysis Systems,” Annu. Rev. Biophys. Biomol. Struct., vol. 29, pp. 155-181, 2000.
Brechtel, R. et al., “Control Of The Electroosmotic Flow By Metal-Salt-Containing Buffers,” Journal of Chromatography A, vol. 716, pp. 97-105, 1995.
Bryzek, Janusz et al., “Micromachines On The March”, IEEE Spectrum, vol. 31, No. 5, pp. 20-31, May 1994.
Buchaillot, Lionel et al., “Silicon Nitride Thin Films Young's Modulus Determination By An Optical Non Destructive Method,” Jpn. J. Appl. Phys., vol. 36, Part 2, No. 6B, pp. L794-L797, Jun. 15, 1997.
Calkins, Kathryn, “Mycometrix: Rubber Chips,” BioCentury, 2 pages, Oct. 16, 2000.
Chang, Jun Keun et al., “Functional Integration Of Serial Dilution And Capillary Electrophoresis On A PDMS Microchip,” Biotechnology and Bioprocess Engineering, vol. 8, No. 4, pp. 233-239, 2003.
Chen, Chihchen et al., “Gray-Scale Photolithography Using Microfluidic Photomasks,” PNAS, vol. 100, No. 4, pp. 1499-1504, Feb. 18, 2003.
Chiu, Daniel T. et al., “Patterned Deposition Of Cells And Proteins Onto Surfaces By Using Three-Dimensional Microfluidic Systems,” PNAS, vol. 97, No. 6, pp. 2408-2413; Mar. 14, 2000.
Chou, Hou-Pu et al., “A Microfabricated Device For Sizing And Sorting DNA Molecules,” Proc. Natl. Acad. Sci., vol. 96, pp. 11-13, Jan. 1999.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Microfluidic chemostat does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microfluidic chemostat, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfluidic chemostat will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4015863

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.