Microfluidic bubble logic devices

Details Microfluidic bubble logic devices Microfluidic bubble logic devices

2011-04-05

2011-04-05

Schneider, Craig M (Department: 3753)

Fluid handling

Flow affected by fluid contact, energy field or coanda effect

Utilizing diverse fluids

Reexamination Certificate

active

07918244

ABSTRACT:
Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, ring oscillators, bubble synchronizers, analysis chips, and printers have been designed.

REFERENCES:
patent: 3894223 (1975-07-01), Majima et al.
patent: 4218761 (1980-08-01), Chen
Hua, Susan Z. et al., “Microfluidic actuation using electrochemically generated bubbles”, Analytical Chemistry, 2002, vol. 74, No. 24, pp. 6392-6386, American Chemical Society.

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