Microfabricated two-pin system for biomolecule crystallization

Details Microfabricated two-pin system for biomolecule crystallization Microfabricated two-pin system for biomolecule crystallization

2006-12-26

2006-12-26

Gordon, Brian (Department: 1743)

Chemistry: analytical and immunological testing

Including sample preparation

Volumetric liquid transfer

C436S174000, C422S105000, C073S864720

Reexamination Certificate

active

07153699

ABSTRACT:
A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two-pin liquid handling system includes a temperature and humidity control element for controlling the temperature of the sample acquisition region to cause transpiration of water to and from a droplet of biomolecule solution to promote crystallization of the biomolecule.

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