Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Patent
1996-04-10
1998-12-01
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
4352872, 435 6, 435970, 435973, 436518, 436524, 436525, 436527, 436805, 436807, 436808, 422 681, 422 8205, 427243, 428426, 428429, C12M 100
Patent
active
058437673
ABSTRACT:
An improved microfabricated apparatus for conducting a multiplicity of individual and simultaneous binding reactions is described. The apparatus comprises a substrate on which are located discrete and isolated sites for binding reactions. The apparatus is characterized by discrete and isolated regions that extend through said substrate and terminate on a second surface thereof such that when a test sample is allowed to the substrate, it is capable of penetrating through each such region during the course of said binding reaction. The apparatus is especially useful for sequencing by hybridization of DNA molecules.
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Dialog abstract of European patent document 0 347 579 (issued above as document AL1), Derwent World Patents Index accession number 90-001005/01.
Dialog abstract of German patent document 38 01 987 (listed above as document AN1), Derwent World Patents Index accession number 89-221475/31.
Bakalyar Heather A.
Houston Advanced Research Center
Hutzell Paula K.
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