Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1996-03-29
1998-02-10
Snay, Jeffrey
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
436177, 436180, 422 81, G01N 2164
Patent
active
057168520
ABSTRACT:
A channel-cell system is provided for detecting the presence and/or measuring the presence of analyte particles in a sample stream comprising: a) a laminar flow channel; b) two inlet means in fluid connection with said laminar flow channel for respectively conducting into said laminar flow channel (1) an indicator stream which may comprise an indicator substance which indicates the presence of said analyte particles by a detectable change in property when contacted with said analyte particles, and (2) said sample stream; c) wherein said laminar flow channel has a depth sufficiently small to allow laminar flow of said streams and a length sufficient to allow particles of said analyte to diffuse into said indicator stream to the substantial exclusion of said larger particles in said sample stream to form a detection area; and d) outlet means for conducting said streams out of said laminar flow channel to form a single mixed stream.
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Brody James P
Holl Mark R.
Weigl Bernhard H.
Yager Paul
Snay Jeffrey
University of Washington
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