Microfabricated differential extraction device and method

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210 961, 210511, 210739, 210748, 216 56, 422 55, 422 69, 436178, B01D 1100, B01D 1104

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059321008

ABSTRACT:
This invention provides a microfabricated extraction system and methods for extracting desired particles from a sample stream containing desired and undesired particles. The sample stream is placed in laminar flow contact with an extraction stream under conditions in which inertial effects are negligible. The contact between the two streams is maintained for a sufficient period of time to allow differential transport of the desired particles from the sample stream into the extraction stream. In a preferred embodiment the differential transport mechanism is diffusion. The extraction system of this invention coupled to a microfabricated diffusion-based mixing device and/or sensing device allows picoliter quantities of fluid to be processed or analyzed on devices no larger than silicon wafers.

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