Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2005-05-10
2005-05-10
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S451000, C424S457000, C424S458000, C424S464000, C424S465000, C424S468000, C424S469000, C424S470000, C424S489000, C424S493000, C424S494000, C424S495000
Reexamination Certificate
active
06890561
ABSTRACT:
There is provided an orally-administrable formulation for the controlled release or stable storage of a granulated isoflavone-enriched fraction or mixture of such fractions, comprising at least one granulated isoflavone-enriched fraction and at least one carrier, diluent or excipient therefor. Preferably, the formulation is characterized in that the total in vitro dissolution time of said formulation required for release of 75% of the active ingredients available from the formulation is between about 4 and about 18 hours, as determined by the U.S.P. XXIII paddle method at a paddle speed of 75 rpm, using simulated intestinal fluid without the digestive enzymes normally found in intestinal fluid, at pH 6.8, and a temperature of 37° C. A process for the preparation of such a formulation is also provided.
REFERENCES:
patent: 4708874 (1987-11-01), De Haan et al.
patent: 5424331 (1995-06-01), Shlyankevich
patent: 5506211 (1996-04-01), Barnes et al.
patent: 5560928 (1996-10-01), DeFelice
patent: 5707353 (1998-01-01), Mazer
patent: 5780060 (1998-07-01), Levy et al.
patent: 5847108 (1998-12-01), Kanaoka et al.
patent: 5985282 (1999-11-01), Haveson
patent: 6004558 (1999-12-01), Thurn et al.
patent: 6117429 (2000-09-01), Bucci
patent: 6248378 (2001-06-01), Ganan-Calvo
patent: 6340478 (2002-01-01), Blatt et al.
patent: 20030175345 (2003-09-01), Hite et al.
patent: 0702957 (1998-12-01), None
patent: 0922450 (1999-06-01), None
patent: 2000351720 (2000-12-01), None
patent: 0020017 (2000-04-01), None
patent: 0030605 (2000-06-01), None
Bauer et al., Coated Pharmaceutical Dosage Forms. Fundamentals, Manufacturing Techniques, Biopharmaceutical Aspects, Test Methods and Row Materials, CRC Press, Washington, D.C. 1998.
Remington's Pharmaceutical Sciences, 8th Edition, Mack Publishing Company, 1990, pp. 1288-1300.
Handbook of Pharmaceutical Excipients, pp. 81-90, 1986, by the American Pharmaceutical Association & Pharmaceutical Society of Great Britain.
USP 24, Test 786, pp. 1969-1970.
Arad Oded
Blatt Yoav
Cohen David
Kimelman Eugene
Pinto Rika
Bio Dar Ltd.
Darby & Darby
Page Thurman K.
Tran S.
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