Microencapsulated agriculturally active material

Chemistry: fertilizers – Processes and products – Forms or conditioning

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71DIG1, A01N 3308, A01N 2528

Patent

active

050731912

ABSTRACT:
Agriculturally active materials, such as pesticides, herbicides and the like and a process for microencapsulating said material. The present invention includes trifluralin having a polymorphic form characterized by a yellow color and a melting point of approximately 41.degree.-43.degree. C. The present invention also includes a method using the yellow polymorphic form of trifluralin as a herbicide. In addition, the present invention includes a method of microencapsulating low-melting agriculturally active materials, such as trifluralin. The microencapsulation process comprises the steps of heating a low-melting, water-immiscible, agriculturally active material to a molten state. The molten active material is then combined with an aqueous solution of a water-soluble, film-forming polymer at a temperature sufficient to maintain the active material in its molten state. The active material is then dispersed or emulsified in the aqueous solution so that the active material has a primary particle size of between approximately 0.1 and 10 microns. The resulting dispersion or emulsion is then spray dried at a temperature between approximately 50.degree. and 220.degree. C. so as to microencapsulate the active material in the polymer. Compounds for promoting the rapid solidification of the active material are also disclosed.

REFERENCES:
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Dumas, J. P. et al. "Phase Transformations in Emulsions: Part II: Polymorphisn for Organic Substances", J. Dispersion Sci. & Tech. 8(1):29-54 (1987).
Bakan, J. A. "Part 3: Microencapsulation" in Leon Lachman et al., The Theory and Practice of Industrial Pharmacy 2nd ed. 1976 p. 427.
Corrigan, O. I. et al. "Physicochemical Properties of Spray Dried Drugs: Phenobarbitone and Hydroflumethiazide"Drug Development and Industrial Pharmacy 9:1-20 (1983).

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