Microcrystalline cellulose cushioning granules

Details Microcrystalline cellulose cushioning granules Microcrystalline cellulose cushioning granules

2005-02-22

2005-02-22

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S124000, C514S054000, C514S057000, C424S457000, C424S458000, C424S465000, C424S489000, C424S490000, C424S494000, C424S496000

Reexamination Certificate

active

06858725

ABSTRACT:
Granulation of microcrystalline cellulose with a granulating fluid consisting of water and a water-miscible, volatile, polar organic solvent yields porous granules which are comprised of particles that are larger than the ungranulated microcrystalline cellulose. This granulated microcrystalline cellulose is capable of cushioning controlled release particles and barrier coated particles from the compression forces used in tableting, thereby maintaining the physical integrity of the components of the tablet.

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