Microcrystalline cellulose/alginate wet granulation excipient/bi

Details Microcrystalline cellulose/alginate wet granulation excipient/bi Microcrystalline cellulose/alginate wet granulation excipient/bi

1998-03-23

1999-11-16

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424489, 514779, 514781, A61K 916, A61K 920

Patent

active

059853239

ABSTRACT:
The present invention discloses an improved excipient composition for use as an excipient/binder for wet granulation of pharmaceuticals, a process for preparing the excipient composition, its use in granular pharmaceutical compositions, and compressed pharmaceutical tablets made from the granular pharmaceutical compositions. The excipient composition comprises a dried aqueous slurry of microcrystalline cellulose wetcake and a low viscosity alginate.

REFERENCES:
patent: 5366742 (1994-11-01), Tuason, Jr. et al.

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