Microcolumnar analytical system with optical fiber sensor

Details Microcolumnar analytical system with optical fiber sensor Microcolumnar analytical system with optical fiber sensor

1995-11-21

1997-07-22

McGraw, Vincent P.

Optics: measuring and testing

By dispersed light spectroscopy

With sample excitation

2504581, 2504591, 356410, G01N 2164, G01N 2105

Patent

active

056508468

ABSTRACT:
An analytical system for analyzing a fluid sample is disclosed. The analytical system includes a microcolumn for conducting the fluid sample, a light source for delivering light through the microcolumnar wall into the microcolumn near the outlet end of that microcolumn, and an optical fiber aligned with the microcolumn to detect light that radiates from the fluid sample without passing through the microcolumnar wall. The microcolumn has an inlet end and an outlet end. A light-inlet end of the optical fiber is nonfixedly coupled to the outlet end of the microcolumn. As the fluid sample is driven from the inlet end to the outlet end of the microcolumn, a light of a suitable wavelength is directed at the microcolumn near its outlet end to cause light interaction with the fluid sample. As a result, light radiates from the fluid sample. This light is collected by the optical fiber to provide information on the presence or quantity of an analyte in the fluid sample.

REFERENCES:
patent: 4675300 (1987-06-01), Zare et al.
patent: 5006210 (1991-04-01), Yeung et al.
patent: 5021646 (1991-06-01), Weinberger et al.
patent: 5114551 (1992-05-01), Hjerten et al.
patent: 5324401 (1994-06-01), Yeung et al.

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