Micrococcus varians strains for producing bactericide compositio

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 712, 424 934, C12N 112

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059812613

ABSTRACT:
Micrococcus varians strains which produce a composition having bactericidal activity, including deposited strains CNCM I-1586 and CNCM I-1587 and biologically pure cultures thereof and including also strains having nucleotide sequence SEQ ID NO:2 or including nucleotides 154 to 228 of sequence SEQ ID NO:2 and which may further include amino acid sequence SEQ ID NO:1 or amino acid sequence SEQ ID NO:3.

REFERENCES:
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Piard et al, "Structure, Organization, and Expression of the lct. gene for Lacticin 481, a Novel Lantibiotic Produced by Lactococcus lactis, " Journal of Biological Chemistry, vol. 286, pp. 16361-16368 (1993).
Piard et al, "Purification and Partial Characterization of Lacticin 481, a Lanthionine-Containing Bacteriocin Produced by Lactococcus lactis, subsp. lactis CNRZ 481" Applied and Environmental Microbiology, vol. 58, pp. 279-284 (1992).
Larsen et al, "Antimicrobial activity of lactic acid bacteria isolated from sour dougs: purification and characterization of bavaracin A, a bacteriocin produced by Lactobacillus bavarious ML401," Journal of Applied Bacteriology, 1993, 75, 113-122.
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Tagg, et al. "Bacteriocins of G ram-Positive Bacteria", 1976, Bacteriol Rev. vol. 40, 1976, pp. 722-756;.
Heatley et al, "The Assay of Micrococcin an almost Insoluble Antibiotic", T. Gen. Microbiol. 6, 30-40, 1952.
Heatley et al., "The Preparation and Some Properties of Purified Micrococcin", Biochem. J. 50:247-253, 1951.
Su, "Antibiotic-Producing Organisms in Faeces and Sewage", Br. J. Exp. Pathol. 29: 466-473, 1948.
Su, "Micrococcin, An Antibacterial Substance Formed by a Strain of Microococcus", Br. J. Exp. Pathol. 29: 473-481, 1948.
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