Microchip method for the enrichment of specific DNA sequences

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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Details

536 243, 935 77, 935 78, C12Q 168, C07H 2104

Patent

active

058517723

ABSTRACT:
A method for enriching specific genetic material sequences is provided, whereby oligonucleotide molecules complementary to the desired genetic material is first used to isolate the genetic material from a first source of genomic material. Then the genetic material is used as a label to isolate similar genetic sequences from other sources.

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patent: 5552278 (1996-09-01), Brenner
Saiki et al., Proc. Natl. Acad. Sci. 86:6230-6234, Aug. 1989.
Matthews et al., Analytical Biochemistry 169:1-25, Feb. 1988.

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