Surgery – Controlled release therapeutic device or system
Reexamination Certificate
2005-04-05
2005-04-05
Casler, Brian L. (Department: 3763)
Surgery
Controlled release therapeutic device or system
C604S891100, C604S093010
Reexamination Certificate
active
06875208
ABSTRACT:
Microchip devices and methods of manufacture thereof are provided to increase the uniformity and reliability of active exposure and release of microchip reservoir contents. In one embodiment, the microchip device for the controlled release or exposure of molecules or secondary devices comprises: (1) a substrate having a plurality of reservoirs; (2) reservoir contents comprising molecules, a secondary device, or both, located in the reservoirs; (3) reservoir caps positioned on the reservoirs over the reservoir contents; (4) electrical activation means for disintegrating the reservoir cap to initiate exposure or release of the reservoir contents in selected reservoirs; and (5) a current distribution means, a stress induction means, or both, operably engaged with or integrated into the reservoir cap, to enhance reservoir cap disintegration.
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Cima Michael J.
Flynn Nolan T.
Maloney John M.
Santini, Jr. John T.
Sbiaa Zouhair
Casler Brian L.
Sutherland & Asbill & Brennan LLP
Williams Catherine S.
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