Microchip and analyzing method and device employing it

Details Microchip and analyzing method and device employing it Microchip and analyzing method and device employing it

2006-08-30

2009-10-20

Thomas, Courtney (Department: 2882)

X-ray or gamma ray systems or devices

Accessory

Object holder or support

C378S079000, C378S047000

Reexamination Certificate

active

07604406

ABSTRACT:
A plurality of elements can be analyzed simultaneously with high sensitivity using a microchip. The microchip (1) comprises a substrate (30), a channel (23) formed in the substrate (30), and an analyzing part (10) consisting of a part of flat surface of the substrate (30), where the outlet of the channel (23) is formed as an opening (9c) and measurement object liquid overflowed from the opening (9c) stays on the flat surface of the substrate (30) to become a sample of analysis. The measurement object liquid is made to overflow as a sample of analysis to the analyzing part (10) using the microchip (1) and then the sample of analysis is preferably dried before a primary X-ray is made to enter under conditions of total reflection and fluorescent X-rays are detected.

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International Preliminary Examination Report for the Application No. PCT/JP2006/317078 dated Nov. 13, 2007.
International Search Report for the Application No. PCT/JP2006/317078 mailed Nov. 21, 2006.
Tsuji, Kouichi et al., “Grazing-Exit and Micro X-ray Fluorescence Analyses for Chemical Microchips”, Analytical Sciences, Jul. 2005, vol. 21, pp. 799-803.
Claes, Martine et al., “Optimization of Sample Preparation for Grazing Emission X-ray Fluorescence in Micro- and Trace Analysis Applications”, Spectrochimica Acta Part B 52, 1997, pp. 1064-1070.

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