Microcavity biosensor and uses thereof

Details Microcavity biosensor and uses thereof Microcavity biosensor and uses thereof

2007-06-05

2007-06-05

Forman, Bj (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S007100, C435S174000, C435S283100, C435S287800, C435S288700, C422S068100, C422S082050, C536S023100, C536S024300, C530S300000, C530S350000

Reexamination Certificate

active

10082634

ABSTRACT:
A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of alternating porosity; and one or more probes coupled to the porous semiconductor structure, the one or more probes binding to a target molecule, whereby a detectable change occurs in a refractive index of the biological sensor upon binding of the one or more probes to the target molecule. Methods of making the biological sensor and methods of using the same are disclosed, as is a detection device which includes such a biological sensor.

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Chan et al., “Nanoscale Silicon Microcavity Optical Sensors for Biological Applications,” Material Research Society Proceedings Symposium F (vol. 638) F.10.4 (2000).
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