Microcapsules prepared by coacervation

Details Microcapsules prepared by coacervation Microcapsules prepared by coacervation

1985-08-26

1989-02-28

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Biocides; animal or insect repellents or attractants

71DIG1, 264 41, 264 43, 264 432, 424418, 424419, 424492, 424496, 424499, 424500, 424DIG10, 42721333, 4284022, H01N 2534, A61K 950, B01J 1302

Patent

active

048084085

ABSTRACT:
There is disclosed an improved complex coacervation process for microencapsulation of core ingredients that are partially soluble in the microcapsule walls wherein the core ingredient is first mixed with a coacervation adjacent prior to forming a first colloidal emulsion of core ingredient, and, after combining the first emulsion with a second colloidal solution and cooling to cause gelation, a water-soluble wax derivative is added. No pH adjustment or dilution is necessary, and very high yields of non-agglomerated microcapsules are obtained, both in terms of quantity of microcapsules and content of core ingredient. When deet is the core ingredient there is obtained a long-lasting mosquito repellent.

REFERENCES:
patent: 3038836 (1962-06-01), Woodard et al.
patent: 3043782 (1962-07-01), Jensen
patent: 3565559 (1971-02-01), Sato et al.
patent: 3956172 (1976-05-01), Saeki et al.
patent: 4298612 (1981-11-01), McGovern et al.

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