Microcapsule for the removal of specific amino acids through the

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Transferases

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424490, 424491, 424 946, A61K 3748, A61K 950

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active

051476410

ABSTRACT:
A microcapsule for oral administration comprising an outer layer membrane which is acid resistant and retains its structure in an alkaline environment, said membrane having dispersed therein at least one enzyme corresponding to an amino acid secreted into the intestinal or derived from a protein or peptide secreted into the intestinal tract. The present invention provides a microcapsule capable of removing specific unwanted amino acids secreted into the intestinal tract.

REFERENCES:
Chang, ed., Biomedical Applications of Immobilized Enzymes and Proteins (7), vol. I, pp. 73-76, 114.
Bourget et al., FEBS Letters, vol. 180 (1), (1985) pp. 5-8.
Edman et al., Biol. Abstracts, vol. 83 (1987) No. 74612.
Article entitled "Plasma/Intestinal Concentration Patterns Suggestive of Entero-Portal Recirculation of Amino Acids . . . " by Thomas M. S. Chang et al., Marcel Dekker, Inc. Biomat., Art. Cells, Org., 16(5) (1989) pp. 915-926.

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