Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Transferases
Patent
1991-06-24
1992-09-15
Stone, Jacqueline
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Transferases
424490, 424491, 424 946, A61K 3748, A61K 950
Patent
active
051476410
ABSTRACT:
A microcapsule for oral administration comprising an outer layer membrane which is acid resistant and retains its structure in an alkaline environment, said membrane having dispersed therein at least one enzyme corresponding to an amino acid secreted into the intestinal or derived from a protein or peptide secreted into the intestinal tract. The present invention provides a microcapsule capable of removing specific unwanted amino acids secreted into the intestinal tract.
REFERENCES:
Chang, ed., Biomedical Applications of Immobilized Enzymes and Proteins (7), vol. I, pp. 73-76, 114.
Bourget et al., FEBS Letters, vol. 180 (1), (1985) pp. 5-8.
Edman et al., Biol. Abstracts, vol. 83 (1987) No. 74612.
Article entitled "Plasma/Intestinal Concentration Patterns Suggestive of Entero-Portal Recirculation of Amino Acids . . . " by Thomas M. S. Chang et al., Marcel Dekker, Inc. Biomat., Art. Cells, Org., 16(5) (1989) pp. 915-926.
Bourget Louis
Chang Thomas M. S.
Lister Colin
Stone Jacqueline
The Royal Institution for the Advancement of Learning (McGill Un
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