Microcantilevers for biological and chemical assays and...

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C204S403060, C204S400000, C436S086000, C436S164000

Reexamination Certificate

active

10422776

ABSTRACT:
Disclosed herein are microcantilevers having structural shapes that are less sensitive to turbulence and drift effects yet provide greater deflections due to analyte concentration. The structural shapes include a C-shaped microcantilever, an E-shaped microcantilever, an L-shaped microcantilever, a double microcantilever, a slit microcantilever, a tapered microcantilever, and a triangular microcantilever. The microcantilevers may be piezoresistive microcantilevers. Also disclosed are microsensors, microfludic devices, and biochips that comprise the microcantilevers as well as methods of using the microcantilevers to detect analytes in a fluid sample.

REFERENCES:
patent: 6325904 (2001-12-01), Peeters
Marie et al, Adsorption kinetics and mechanical properties of thiol-modified DNA-oligos on gold investigated by microcantilever sensors, May 2002, Ultramicroscopy, 91, 29-36.
Bergaud et al, Finite element calculations and fabrication of cantilever sensors for nanoscale detection, Oct. 2001, Emerging Technologies and Factory Automation, 2001. Proceedings, 82, 69-77.
Chen et al. (1994) “Resonance response of scanning force microscopy cantilevers” Rev. Sci. Instrum. 65(8):2532-2537.
Cowburn et al. (1997) “High sensitivity measurement of magnetic fields using microcantilevers” Appl. Phys. Lett. 71(15):2202-2204.
Datskos and Sauers (1999) “Detection of 2-mercaptoethanol using gold-coated micromachined cantilevers” Sensors and Actuators B 61:75-82.
Godin et al. (2001) “Quantitative surface stress measurements using a microcantilever” Appl. Phys. Lett., 79(4):551-553.
Grogan et al. (2002) “Characterisation of an antibody coated microcantilever as a potential immuno-based biosensor” Biosensors & Bioelectronics 17:201-207.
Hansen et al. (2001) “Cantilever-Based Optical Deflection Assay for Discrimination of DNA Single-Nucleotide Mismatches” Anal. Chem. 73:1567-1571.
Khaled and Vafai (2002) “Flow and heat transfer inside thin films supported by soft seals in the presence of internal and external pressure pulsations”International Journal of Heat and Mass Transfer 45:5107-5115.
Khaled and Vafai (2003) “Heat transfer and hydromagnetic control of flow exit conditions inside oscillatory squeezed thin films” Numerical Heat Transfer, Part A 43:239-258.
Khaled and Vafai (2003) “Analysis of flow and heat transfer inside oscillatory squeezed thin films subject to a varying clearance” International Journal of Heat and Mass Transfer 46:631-641.
Khaled et al. (2003) “Analysis, control and augmentation of microcantilever deflections in biosensing systems” Sensors and Actuators B 94:103-115.
Moulin et al. (1997) “Micromechanical thermal sensors: Comparison of experimental results and simulations” J. Vac. Sci. Technol. B 15(3):590-596.
Shi (2003) “Cantilever optical vibrometer using fiber Bragg grating” Opt. Eng. 42(11):3179-3181.

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