Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1990-08-16
1991-08-06
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
424630, A61K 716, A61K 3334
Patent
active
050376330
ABSTRACT:
The invention provides a process for microbiologically stabilizing a premix phase intended to receive bicarbonate in the manufacture of toothpaste. The process includes blending together in the premix phase a polyol, a thickening agent, a copper compound and water. The premix phase is maintained at a temperature no higher than 110.degree. F. for a time sufficient to destroy bacteria. Thereafter the bicarbonate is incorporated into the premix phase without cool-down of the premix phase. There is also disclosed an oral composition that includes a combination of humectant, thickening agent, copper, bicarbonate and water.
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"Stabilisation, Disinfection, Preservation", Textbook edited by S. S. Block (1983), Chapter 11 by F. J. Turner, pp. 240-250.
Williams David R.
Ziemkiewicz Alexander G.
Chesebrough-Pond's USA Co. Division of Conopco, Inc.
Honig Milton L.
Rose Shep K.
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