Microbiologically produced d(-)-mandelate-dehydrogenase process

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435190, 435853, C12P 742, C12N 904, C12R 1225

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active

048247812

ABSTRACT:
The subject matter of the invention is a new D(-)-mandelate-dehydrogenase and obtaining it from Lactobacillus curvatus DSM 20019 (obtainable from the German Collection of Microorganisms). The new enzyme can be used for the enzymatic conversion of D(-)-mandelic acid and various other D-2-hydroxycarboxylic acids into the corresponding 2-ketocarboxylic acids or from benzoyl formate and various other 2-ketocarboxylic acids conversion to the corresponding D-2-hydroxycarboxylic acids.

REFERENCES:
patent: 4609623 (1986-09-01), Leuchtenberger et al.
Bergly Manual of Systematic Bacteriology vol. 2 (1986), Sneath, et al., editors, Williams & Wilkins, Baltimore, pp. 1226 & 1228.

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