Microbiologically produced D-2-hydroxy-4-methylpentanoic acid de

Details Microbiologically produced D-2-hydroxy-4-methylpentanoic acid de Microbiologically produced D-2-hydroxy-4-methylpentanoic acid de

1984-06-06

1986-09-02

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing sulfur-containing organic compound

435136, 435146, 435189, 435190, 435853, 435856, 435822, C12P 1100, C12P 740, C12P 742, C12N 902, C12N 904, C12R 1225, C12R 1245, C12R 101

Patent

active

046096230

ABSTRACT:
The enzyme D-2-hydroxy-4-methylpentanoic acid dehydrogenase has been prepared by culturing readily available Lactobacillus or Leuconostoc, microorganisms, such as Lactobacillus casei ssp. pseudoplantarum and Leuconostoc mesenteroides. The microbiologically produced enzyme has special characteristics and is capable of converting D-2-hydroxycarboxylic acids, such as D-2-hydroxy-4-methylpentanoic acid to the corresponding 2-ketocarboxylic acid and is capable of enzymatically converting 2-ketocarboxylic acids, such as 2-keto-4-methylpentanoic acid and 2-ketobutyric acid to the corresponding D-2-hydroxycarboxylic acid.

REFERENCES:
patent: 4326031 (1982-04-01), Wandrey et al.
patent: 4530903 (1985-07-01), Leuchtenberger et al.

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