Microbiological reduction of PGA.sub.2 and 15-epi PGA.sub.2

Details Microbiological reduction of PGA.sub.2 and 15-epi PGA.sub.2 Microbiological reduction of PGA.sub.2 and 15-epi PGA.sub.2

1975-04-04

1976-01-06

Tanenholtz, Alvin E.

Textiles: fiber preparation

195 30, C12D 102

Patent

active

039309525

ABSTRACT:
Reduction of 7(2-[(3R and 3S)-3-hydroxy-1-octenyl]-5-oxo-3-cyclopenten-1-yl)-5-heptenoic acid by microorganisms of the genera Streptomyces, Pseudomonas and Corynebacterium is disclosed. The products 7-(2-[(3R)-3-hydroxy-1-octenyl]-5-oxo-cyclopentyl)-5-heptenoic acid(11-deoxy-15-epi-PGE.sub.2), which is novel, and 7-(2-[(3S)-3-hydroxy-1-octenyl]-5-oxo-3-cyclopentyl)-5-heptenoic acid(11-deoxy-PGE.sub.2), respectively, are useful as intermediates for the synthesis of other physiologically active ingredients.

REFERENCES:
patent: 3788947 (1974-01-01), Hsu et al.

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