Microbiological process for the production of hydroxylated pyraz

Details Microbiological process for the production of hydroxylated pyraz Microbiological process for the production of hydroxylated pyraz

1991-11-06

1992-12-22

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

4352522, 435822, C12P 1712, C12R 101

Patent

active

051734125

ABSTRACT:
Microorganisms, which are capable of growing with pyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate pyrazine derivatives of general formula: ##STR1## to hydroxylated pyrazine derivatives of general formula: ##STR2## and the latter are accumulated in the growth medium.

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Karmas and Spoerri, J. Amer. Chem Soc., 74 (1952), pp. 1580-1584.
MacDonald, J. C., Bishop, G. C., Mazurek, Tetrahedron, 32, (1976) pp. 655 to 660.

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