Microbiological process for the production of 7-substituted...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

Reexamination Certificate

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Reexamination Certificate

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10625559

ABSTRACT:
A novel method of synthesis for the manufacture of upstream products for the production of compounds with general formulas 8, 10, and 12 is described. In this synthesis, compounds with general formula 4,B are produced in a microbiological reaction. The meanings of R7, R10, R11, R13, R17and R17′as well as of the grouping U—V—W—X—Y—Z are indicated in the claims

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patent: WO99/13812 (1999-03-01), None
patent: WO 02/059139 (2002-08-01), None
patent: WO 2004/011008 (2004-02-01), None
Tan L et al., “Interactions of Steroids and Fungi. 11 Alpha-hydroxylation and Degradation. of Progestrone-4-C by a Cell-free Preparation from Aspergillus Ochraceus,” Journal of Steroid Biochemistry, Sep. 1, 1970, pp. 221-227, vol. 1, No. 3, XP000671122, ISSN: 0022-4731, the entire document, Pergamon Press PLC, GB.
Shibahara M et al., “Microbial Hydroxylations V. lialpha-hyroxylation of Progestrone by cell-free preparations of Aspergillus Ochraceus,” Biochimica Et Biophysica Acta, 1970, pp. 172-179, vol. 202, XP009023368, ISSN: 0006-3002, the entire document, Amsterdam, NL.

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