Microbiological degradation of sterol side chains to a 17-keto g

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

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435863, C07B 2902

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active

041793366

ABSTRACT:
The side chains of sterols are degraded by fermentation with microorganisms capable of doing so in an improved manner by employing in such fermentations sterol derivatives of the formula ##STR1## wherein n is 1 or 2; R.sub.1 is H or lower alkyl, R.sub.2 is alkyl, whose chain optionally is interrupted by an oxygen atom, or when n is 2, also a hydrogen atom; and R.sub.3 is a sterol side chain.

REFERENCES:
patent: 3451892 (1969-06-01), Herzog et al.
patent: 3684656 (1972-08-01), Waard
Buki et al., Acta Microbiol. Acad. Sci., Hung. 22, 447-451 (1975).

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