Microbial transformation product having immunosuppressive activi

Details Microbial transformation product having immunosuppressive activi Microbial transformation product having immunosuppressive activi

1993-06-09

1994-10-04

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

435119, C07D49116, A61K 31345, C12P 1714

Patent

active

053527836

ABSTRACT:
Microbial transformation of a macrolide immunosuppressant by the microorganism Streptomyces sp., (Merck Culture Collection MA 6960) ATCC No. 55387 yields a compound of the structural formula (I): ##STR1## This compound is an immunosuppressant useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases, the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.

REFERENCES:
patent: 3244592 (1966-04-01), Arai
patent: 4894366 (1990-01-01), Okuhara et al.
patent: 4975372 (1990-12-01), Arison et al.
patent: 4987139 (1991-01-01), Chen et al.
patent: 5138052 (1992-08-01), Chen et al.

Affiliated with

Also associated with

Rating

Microbial transformation product having immunosuppressive activi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microbial transformation product having immunosuppressive activi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microbial transformation product having immunosuppressive activi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-582381