Microbial process for the production of trans-4-hydroxy-L-prolin

Details Microbial process for the production of trans-4-hydroxy-L-prolin Microbial process for the production of trans-4-hydroxy-L-prolin

1992-12-15

1994-08-02

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435122, 435822, C12P 1710, C12P 1712

Patent

active

053345177

ABSTRACT:
Trans-4-hydroxy-L-proline is produced microbially, especially by the cultivation of a microorganism of the genus Clonostachys, Gliocladium or Nectria.

REFERENCES:
Tomoyuki Shibata et al., Heterocycles, An International Journal for Reviews and Communications in Heterocyclic Chemistry, "Synthesis of Optically Active 3-Mercapto pyyrolidine Derivatives, Synthetic Intermediates of Carbapenem RS-533 and Its Isomer" (1986), 24, No. 5.
Ramadasan Kuttan et al., "The Biosynthesis of Cis-4-Hydroxy-L-proline in Sandal", Biochem. J., 117, 1013 (1970), pp. 1015-1017.

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