Microbial process for producing cholanic acid derivatives

Details Microbial process for producing cholanic acid derivatives Microbial process for producing cholanic acid derivatives

1980-07-30

1982-11-16

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435253, 435830, 435840, 435843, C12P 3300

Patent

active

043595294

ABSTRACT:
A microbial process for producing a cholanic acid derivative of the formula: ##STR1## wherein X is ##STR2## or .dbd.O; and R is hydrogen, an alkali metal or an alkaline earth metal, which comprises cultivating a microbe which is capable of growing in a medium containing cholic acid or a salt thereof as a substrate to produce the cholanic acid derivative, selected from the genera Arthrobacter, Brevibacterium and Corynebacterium, in a culture medium containing the substrate and collecting the resulting derivative.

REFERENCES:
patent: 2360447 (1944-10-01), Schmidt et al.
Lamanna et al., Basic Bacteriology, 3rd Ed. The Williams & Wilkins Co., 1965, pp. 721-726.
Metzler, Biochemistry, The Chemical Reactions of Living Cells, Academic Press Inc. pp. 945, 946 (1977).

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