Microbial oils produced in transformed host cells comprising...

Details Microbial oils produced in transformed host cells comprising... Microbial oils produced in transformed host cells comprising...

2009-11-17

2011-11-01

Fronda, Christian (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

C435S183000, C435S193000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

08048653

ABSTRACT:
The present invention relates to Δ9 elongases, which have the ability to convert linoleic acid [18:2, LA] to eicosadienoic acid [20:2, EDA]. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ9 elongase along with methods of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ9 elongases in plants and oleaginous yeast are disclosed.

REFERENCES:
patent: 6825017 (2004-11-01), Browse et al.
patent: 0034439 (2000-06-01), None
patent: WO 00/34439 (2000-06-01), None
patent: 02/077213 (2002-10-01), None
patent: 02077213 (2002-10-01), None
patent: WO 02/077213 (2002-10-01), None
patent: WO 02/077213 (2002-10-01), None
patent: 2004/057001 (2004-07-01), None
patent: 2004057001 (2004-07-01), None
patent: WO 2004/057001 (2004-07-01), None
patent: 2004071178 (2004-08-01), None
patent: 2004071467 (2004-08-01), None
patent: WO 2004/071178 (2004-08-01), None
patent: WO 2004/071467 (2004-08-01), None
patent: 2004101753 (2004-11-01), None
patent: 2004101757 (2004-11-01), None
patent: WO 2004/101753 (2004-11-01), None
patent: WO 2004/101757 (2004-11-01), None
patent: 2005012316 (2005-02-01), None
patent: WO 2005/012316 (2005-02-01), None
patent: 2005083093 (2005-09-01), None
patent: WO 2005/083093 (2005-09-01), None
patent: 2005103253 (2005-11-01), None
patent: WO 2005/103253 (2005-11-01), None
patent: 2006012325 (2006-02-01), None
patent: 2006012326 (2006-02-01), None
patent: WO 2006/012325 (2006-02-01), None
patent: WO 2006/012326 (2006-02-01), None
patent: 2006052870 (2006-05-01), None
patent: 2006052871 (2006-05-01), None
patent: 2006055322 (2006-05-01), None
patent: WO 2006/052870 (2006-05-01), None
patent: WO 2006/052871 (2006-05-01), None
patent: WO 2006/055322 (2006-05-01), None
U.S. Appl. No. 10/840,478, filed Dec. 16, 2004, Picataggio et al.
U.S. Appl. No. 10/840,579, filed Jun. 23, 2005, Picataggio et al.
U.S. Appl. No. 10/840,325, filed Feb. 24, 2005, Yadav et al.
U.S. Appl. No. 10/869,630, filed Jan. 20, 2005, Picataggio et al.
U.S. Appl. No. 10/882,760, filed Jul. 20, 2006, Yadav et al.
U.S. Appl. No. 10/985,109, filed Jun. 16, 2005, Damude et al.
U.S. Appl. No. 10/985,691, filed Sep. 29, 2005, Yadav et al.
U.S. Appl. No. 10/987,548, filed Jun. 16, 2005, Walters Pollak.
U.S. Appl. No. 11/024,545, filed May 4, 2006, Xue et al.
U.S. Appl. No. 11/024,544, filed May 4, 2006, Yadav et al.
U.S. Appl. No. 11/166,993, filed Dec. 29, 2005, Damude et al.
U.S. Appl. No. 11/183,664, filed Jan. 26, 2006, Picataggio et al.
U.S. Appl. No. 11/185,301, filed May 4, 2006, Xue et al.
U.S. Appl. No. 11/190,750, filed May 4, 2006, Picataggio et al.
U.S. Appl. No. 11/198,975, filed Aug. 8, 2005, Zhu et al.
U.S. Appl. No. 11/225,354, filed Mar. 16, 2006, Xue et al.
U.S. Appl. No. 11/251,466, filed May 4, 2006, Damude et al.
U.S. Appl. No. 11/254,173, filed May 4, 2006, Macool et al.
U.S. Appl. No. 11/253,882, filed Apr. 19, 2007, Macool et al.
U.S. Appl. No. 11/264,784, filed May 4, 2006, Damude et al.
U.S. Appl. No. 11/264,737, filed May 25, 2006, Damude et al.
U.S. Appl. No. 11/265,761, filed Jun. 1, 2006, Damude et al.
U.S. Appl. No. 60/739,989, filed Nov. 23, 2005, Damude et al.
U.S. Appl. No. 60/795,810, filed Apr. 28, 2006, Damude et al.
U.S. Appl. No. 60/793,575, filed Apr. 20, 2006, Xue et al.
U.S. Appl. No. 60/796,637, filed May 1, 2006, Yadav et al.
U.S. Appl. No. 60/801,172, filed May 17, 2006, Damude et al.
U.S. Appl. No. 60/801,119, filed May 17, 2006, Damude et al.
U.S. Appl. No. 60/853,563, filed Oct. 23, 2006, Damude et al.
U.S. Appl. No. 60/855,177, filed Oct. 30, 2006, Xue et al.
U.S. Appl. No. 10/776,311, filed Sep. 2, 2004, Cahoon et al.
U.S. Appl. No. 10/776,889, filed Feb. 11, 2004, Kinnay et al.
U.S. Appl. No. 11/166,003, filed Aug. 31, 2006, Damude et al.
J. Dyerberg et. al., Fatty Acid Composition of the Plasma Lipids in Greenland Eskimos, Amer. J. Clin. Nutr., 1975, vol. 28:958-966.
J. Dyerberg et. al., Eicosapentaenoic Acid and Prevention of Thrombosis and Atherosclerosis, Lancet, 1978, vol. 2:117-119.
H. Shimokawa, Beneficial Effects of Eicosapentaenoic Acid on Endothelial Vasodilator Functions in Animals and Humans, World Rev. Nutr. Diet, 2001, vol. 88:100-108.
C. Schacky et. al., 3 Fatty Acids—From Eskimos to Clinical Cardiology—What Took Us So Long? World Rev. Nutr. Dirt, 2001, vol. 88:90-99.
National Center for Biotechnology Information General Identifier No. AAL37626, Mar. 9, 2006, B. Qi Et. Al., Identification of a CDNA Encoding a Novel C18-Delta (9) Polyunsaturated Fatty Acid-Specific Elongating Activity From the Docosahexaenoic Acid (DHA)-Producing Microalga, Isochrysis Galbana.
Browse et. al., Polyunsaturated Fatty Acids Synthesis: What Will They Think of Next?, Trends in Biochemical Sciences, 2002, vol. 27:467-473.
Napier, Plumbing the Depths of PUFA Biosynthesis: A Novel Polyketide Synthase-Like Pathway From Marine Organisms, Trends in Plant Sciences, 2002, vol. 7:51-54.
Wallis et. al., The Desaturase ofEuglena Gracilis: An Alternate Pathway for Synthesis of 20-Carbon Polyunsaturated Fatty Acids, Arch. Biochem. and Biopys., 1999, vol. 365:307-316.
Sayanova et. al., The Alternative Pathway C20, 8 Desaturase From the Non-Photosynthetic Organism Acanthamoeba Castellanii is an Atypical Cytochrome B5-Fusion Desaturase, FEBS Lett., 2006, vol. 580:1946-1952.
Qi, Baoxiu et al., Identification of a cDNA encoding a novel C18-Delta9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga,Isochrysis galbanal1, FEBS Letters, 2002, p. 159-165, vol. 510.
Qi, Baoxiu et al, Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants, Nature Biotechnology, Jun. 2004, p. 739-745, vol. 22, No. 6.
Beaudoin, Frederic et al., Heterologous reconstitution in yeast of the polyunsaturated fatty acid biosynthetic pathway, PNAS, Jun. 6, 2000, p. 6421-6426, vol. 97, No. 12.
Barsanti, Laura et al., Fatty acid content in wild type and WZSL mutant ofEuglena gracilis, Journal of Applied Phycology, 2000, p. 515-520, vol. 12, Kluwer Academic Publishers.
Drexler, Hjordis et al., Metabolic engineering of fatty acids for breeding of new oilseed crops: strategies, problems and first results, Journal of Plant Physiology, 2003, p. 779-802, Urban & Fischer Verlag.
U.S. Appl. No. 10/840,478, filed Dec. 16, 2004, Stephen K. Picataggio et al.
U.S. Appl. No. 10/840,579, filed Jun. 23, 2005, Stephen K. Picataggio et al.
U.S. Appl. No. 10/840,325, filed Feb. 24, 2005, Narendra S. Yadav et al.
U.S. Appl. No. 10/869,630, filed Jan. 20, 2005, Stephen K. Picataggio et al.
U.S. Appl. No. 10/882,760, filed Jul. 20, 2006, Narendra S. Yadav et al.
U.S. Appl. No. 10/985,109, filed Jun. 16, 2005, Howard Glenn Damude et al.
U.S. Appl. No. 10/985,691, filed Sep. 29, 2005, Narendra S. Yadav et al.
U.S. Appl. No. 10/987,548, filed Jun. 16, 2005, Dana M. Walters Pollak.
U.S. Appl. No. 11/024,545, filed May 4, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/024,544, filed May 4, 2006, Narendra S. Yadav et al.
U.S. Appl. No. 11/166,993, filed Dec. 29, 2005, Howard Glenn Damude et al.
U.S. Appl. No. 11/183,664, filed Jan. 26, 2006, Stephen K. Picataggio et al.
U.S. Appl. No. 11/185,301, filed May 4, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/190,750, filed May 4, 2006, Stephen K. Picataggio et al.
U.S. Appl. No. 11/198,975, filed Aug. 8, 2005, Quinn Qun et al.
U.S. Appl. No. 11/225,354, filed Mar. 16, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/251,466, filed May 4, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/254,173, filed May 4, 2006, Daniel Joseph Macool et al.
U.S. Appl. No. 11/253,882, filed Apr. 19, 2007, Daniel Joseph Macool et al.
U.S. Appl. No. 11/264,784, filed May 4, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/264,737, filed May 25, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/265,761, filed Jun. 1, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/739,989, filed Nov. 23, 2005, Howard Glenn Damude et al.
U.S. Appl. No. 60/795,810, filed Apr. 28, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/793,575, filed Apr. 20, 2006,

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