Microbial n-and o-demethylation of a thebaine derivative

Details Microbial n-and o-demethylation of a thebaine derivative Microbial n-and o-demethylation of a thebaine derivative

2007-09-11

2007-09-11

Barts, Samuel (Department: 1621)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

C435S254100

Reexamination Certificate

active

10512746

ABSTRACT:
The invention provides a process for the N-demethylation or the N- and O-demethylation of a thebaine derivative which process comprises fermenting the derivative with a biocatalyst selected from the filamentous fungi fromCunninghamella dalmaticaNRRL 1394,Cunninghamella echinulataNRRL 1387,Cunninghamella echinulataNRRL 1384,Cunninghamella echinulataATCC 36190,Cunninghamella echinulataATCC 11585a,Cunninghamella echinulataATCC 9244,Cunninghamella polymorphaNRRL 1395, orRhizopus nigricansZ5/1in a basal fermentation medium at a temperature of at least 25° C. and not more than 34° C., for a period of time of at least 3 days.

REFERENCES:
patent: 3433791 (1969-03-01), Bentley
patent: 558 362 (1974-12-01), None
patent: 2 554 816 (1985-05-01), None
patent: WO89/00203 (1989-01-01), None
patent: WO97 44317 (1997-11-01), None
International Search Report dated Jul. 23, 2003 for Application No. PCT/GB03/01735.
International Preliminary Examination Report dated Dec. 29, 2003 for Application No. PCT/GB03/01735.
Combined Search and Examination Report from The Patent Office in Great Britain dated Oct. 17, 2002 for Application No. GB 0210638.3.
Shanghui Hu et al.; “Microbial Transformation of Taxoids: Selective Deacetylation and Hydroxylation of 2α, 5α, 10β, 14β-Tetra-acetoxy-4(20), 11-taxadiene by the FungusCunninghamella echinulata”; Tetrahedron.; vol. 52; No. 26; pp. 8739-8746; 1996; XP004103817; Elsevier Science Publishers, Amsterdam, NL; ISSN: 0040-4020.
J. Marton et al.; “Herstellung von 6,14-Ethenomophinan-Derivaten”; Monatshefte Fuer Chemie.; vol. 125; pp. 1229-1239; 1994; XP002208720; Springer Verlag, Vienna, At; ISSN: 0026-9247.

Affiliated with

Also associated with

Rating

Microbial n-and o-demethylation of a thebaine derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microbial n-and o-demethylation of a thebaine derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microbial n-and o-demethylation of a thebaine derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3749423